What is a very mild antidepressant?
Daniel Rodriguez
Published Mar 11, 2026
What is a very mild antidepressant?
Bupropion (Aplenzin, Wellbutrin) is a unique antidepressant that is thought to affect the brain chemicals norepinephrine and dopamine. Side effects are usually mild, including upset stomach, headache, insomnia, and anxiety. Bupropion may be less likely to cause sexual side effects than other antidepressants.
What is the best antidepressant for anxiety with the least side effects?
Tricyclic antidepressants Tricyclic antidepressants (TCAs) are an older class of antidepressant drug. Although they may be effective for the treatment of depression and anxiety, doctors often prescribe SSRIs instead, as they cause fewer side effects.
What is the weakest antidepressant?
Those that made the least-effective list of antidepressant drugs sold in the United States included: Luvox (fluvoxamine) Oleptro (trazodone) Prozac (fluoxetine)
What is the safest antidepressant for anxiety?
Readers rate antidepressants
| Drug class | Effectiveness | Side affects |
|---|---|---|
| Helped a lot | Difficulty stopping the drug | |
| SSRIs (Celexa, Lexapro, Prozac, Zoloft) | 53% | 8% |
| SNRIs (Cymbalta, Effexor) | 49 | 13 |
| Bupropion (Wellbutrin) | 48 | 5 |
What is the mildest anti-anxiety med?
Buspirone, also known by the brand name BuSpar, is a newer anti-anxiety drug that acts as a mild tranquilizer. Buspirone relieves anxiety by increasing serotonin in the brain—as the SSRIs do—and decreasing dopamine. Compared to benzodiazepines, buspirone is slow acting—taking about two weeks to start working.
What is the safest anti-anxiety drug?
As of this writing, some of the anxiety medications with the fewest reported side effects and least risk of side effects include:
- Most Benzodiazepines (Xanax, Valium)
- Bupropion (Wellbutrin)
- Citalopram (Celexa – SSRI)
- Paroxetine (Paxil – SSRI)
What is the #1 antidepressant?
Zoloft is the most commonly prescribed antidepressant; nearly 17% of those surveyed in the 2017 antidepressant use study reported that they had taken this medication. 3. Paxil (paroxetine): You might be more likely to have sexual side effects if you choose Paxil over other antidepressants.
What is the best antidepressant for energy and motivation?
Prozac/Fluoxetine It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression. That being said, for those with low energy, it can be helpful. Fluoxetine treats many mental health issues which includes depression, OCD, and panic disorders.
