What does it mean if you test positive for hep C antibodies?
John Castro
Published Feb 09, 2026
What does it mean if you test positive for hep C antibodies?
A reactive or positive antibody test means you have been infected with the hepatitis C virus at some point in time. Once people have been infected, they will always have antibodies in their blood. This is true if they have cleared the virus, have been cured, or still have the virus in their blood.
Where can I get tested for Hep C antibodies?
GP surgeries, sexual health clinics, genitourinary medicine (GUM) clinics or drug treatment services all offer testing for hepatitis C.
How accurate is Hep C antibody test?
According to a 2016 review , third-generation anti-HCV tests have an average specificity of 97.5% to 99.7%. The sensitivity of these tests varies from 61.0% to 81.8%. These findings indicate that anti-HCV tests detect true negatives (specificity) more accurately than true positives (sensitivity).
Do hep C antibodies ever go away?
Unfortunately, the antibody is with the patient for life. It does NOT go away. The viral load becomes undetected.
Can I donate blood if I have Hep C antibodies?
No, you cannot donate blood if you ever had hepatitis C, even if you spontaneously cleared the virus or if you were successfully cured with medication.
Are hep C antibodies contagious?
Hepatitis C is a contagious liver disease caused by the hepatitis C virus (HCV). The disease can be passed from person to person. As with many infections, HCV lives in blood and bodily fluids.
What is a PCR test for Hep C?
The PCR (polymerase chain reaction) test determines whether you are currently infected by detecting the presence of the genetic material of the virus in the blood. This genetic material is called RNA and this test is sometimes referred to as an RNA test.
How do you test for Hep C viral load?
Overview. The HCV RNA PCR test is used to determine whether the hepatitis C virus (HCV) exists in your bloodstream. If the virus is present, the test can also measure the exact amount that’s in your blood. The amount of virus in your blood is known as the viral load.
What does an inconclusive hep C test mean?
INCONCLUSIVE ANTI-HCV OR LOW RNA RESULTS: Inconclusive anti-HCV antibody results are considered negative for hepatitis C, unless the concurrent RNA is positive, in which case the inconclusive anti-HCV antibody result is considered positive for hepatitis C. • RNA result <15 IU per ml are considered RNA positive.
Can Hep C be misdiagnosed?
False-positive results appear to be common. According to a 2017 report , 22 percent of 479 subjects received a false-positive anti-HCV test. According to a 2020 report, the rate of false-positive test results among 1,814 reactive serum samples was 10 percent.
When do hep C antibodies show up?
If a person exposed to hepatitis C becomes infected, virus particles (called HCV RNA) can be detected within 1-2 weeks. Liver function tests also tend to rise during this timeframe. Hepatitis C antibodies appear after RNA is detectable and can take 3-12 weeks to appear.
Why hepatitis C tests may give false results?
This phenomenon is known as cross-reactivity, and it often results in a false positive. The results may be verified through an RNA test. People who have recovered from hepatitis C on their own may also get a false-positive ELISA test result. In rare cases, lab error leads to a false positive.
What is the life expectancy of someone with hepatitis C?
Life expectancy for someone with hep c is just the same as for someone without. Life expectancy for someone diagnosed with compensated Cirrhosis is around 15-20 years, once you decomp about 1/2 will be dead within 2 years. The easiest way to get Cirrhosis is to have hep c and drink alcohol.
Who should get tested for hepatitis C?
Currently, it is recommended that all adults age 18-79 be tested for hepatitis C. Talk to your VA provider about risk factors that may require more regular screening. The hepatitis C test is available for all Veterans enrolled in VA health care. See the printable HCV testing handout for information about getting tested at a VA facility.
Is it possible to get a false positive for hepatitis C?
People who have recovered from hepatitis C on their own may also get a false-positive ELISA test result. In rare cases , lab error leads to a false positive . False-positive results may also occur in newborns who carry HCV antibodies from their mothers.