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What conditions cause Lymphocytopenia?

Author

Christopher Anderson

Published Mar 17, 2026

What conditions cause Lymphocytopenia?

Lymphocytopenia is most often due to AIDS, and recently COVID-19, or undernutrition, but it also may be inherited or caused by various infections, drugs, or autoimmune disorders. Patients have recurrent viral, fungal, or parasitic infections. Lymphocyte subpopulations and immunoglobulin levels should be measured.

What is the ICD 10 code for lymphopenia?

D72. 810 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What does Lymphocytopenia mean?

Listen to pronunciation. (LIM-foh-PEE-nee-uh) A condition in which there is a lower-than-normal number of lymphocytes (a type of white blood cell) in the blood. Also called lymphocytic leukopenia and lymphocytopenia.

What is Wiskott Aldrich?

Wiskott-Aldrich syndrome is a rare genetic disorder of the immune system that primarily affects boys. It is characterized by abnormal immune function and a reduced ability to form blood clots.

What autoimmune diseases cause low lymphocytes?

Lymphopenia is not uncommon in several human autoimmune diseases. Reduced total lymphocyte counts are observed in rheumatoid arthritis, insulin-dependent diabetes mellitus, Crohn’s disease, systemic lupus erythematosus (SLE) and primary vasculitides.

Why do viral infections cause lymphopenia?

Cell Death. Lymphocyte death plays a critical role in lymphopenia caused by many viral infections (Table 1). Apoptosis, pyroptosis, autophagy, virus-specific CD8+ cytotoxic T lymphocyte (CTL) dependent killing and antibody-dependent cell-mediated cytotoxicity (ADCC) were reported to be involved in lymphopenia.

What is the ICD-10 code for leukopenia?

D72.819
819 for Decreased white blood cell count, unspecified is a medical classification as listed by WHO under the range – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

What is the medical term for low white blood cell count?

A low white blood cell count (leukopenia) is a decrease in disease-fighting cells (leukocytes) in your blood. Leukopenia is almost always related to a decrease in a certain type of white blood cell (neutrophil). The definition of low white blood cell count varies from one medical practice to another.

What is the difference between lymphopenia and leukopenia?

In fact, some people use the terms “leukopenia” and “neutropenia” interchangeably. Another common type of leukopenia is lymphocytopenia, which is when you have too few lymphocytes. Lymphocytes are the WBCs that protect you from a variety of infections and also from cancerous cells.

What is mild lymphocytopenia?

Lymphocytopenia, also referred to as lymphopenia, occurs when your lymphocyte count in your bloodstream is lower than normal. Severe or chronic low counts can indicate a possible infection or other signficant illness and should be investigated by your doctor. Lymphocytes are a kind of white blood cell.

Why is there thrombocytopenia in Wiskott-Aldrich syndrome?

The Wiskott-Aldrich syndrome (WAS) is an X-linked hereditary disease characterized by thrombocytopenia with small platelet size, eczema, and increased susceptibility to infections. The gene responsible for WAS was recently cloned.

Is immunocompromised the same as immunodeficiency?

A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised individual may particularly be vulnerable to opportunistic infections, in addition to normal infections that could affect anyone.