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How many NMR signals are in aspirin?

Author

Robert Miller

Published Feb 21, 2026

How many NMR signals are in aspirin?

six peaks
The NMR spectrum of aspirin has six peaks.

Which region is used in NMR spectroscopy?

Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei….J-coupling.

MultiplicityIntensity ratio
Septet1:6:15:20:15:6:1

What is the chemical shift of the acetyl proton in the pure aspirin?

11.77 ppm
Aspirin contains aliphatic, aromatic and carboxylic acid protons that span a wide range of the 1H spectrum, and signal integration reveals a 3:4:1 intensity distribution, respectively. The carboxylic acid resonance (O=COH) is identified by a characteristic downfield chemical shift at 11.77 ppm.

What will be the primary differences in the H NMR of salicylic acid and aspirin?

The difference between aspirin and salicylic acid is presence of carboxylic ester in aspirin and -OH in salicylic acid. Aspirin show peaks at 1790, 1240, and 1090 cm-1for carboxylic ester which is not present in salicylic acid.

What’s the chemical in aspirin?

The Chemistry of Aspirin (acetylsalicylic acid) Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.

What is the chemical shift δ in NMR spectroscopy?

In nuclear magnetic resonance (NMR) spectroscopy, the chemical shift is the resonant frequency of a nucleus relative to a standard in a magnetic field. Often the position and number of chemical shifts are diagnostic of the structure of a molecule.

How many different signals would you expect on the 1h and 13c NMR spectra of aspirin?

There are 6 signals expected in^1HNMR spectrum.

What is Iupac name and structure of aspirin?

Aspirin: Summary in Tabular Form

Aspirin
Chemical formulaCH3COOC6H4COOH or C9H8O4
IUPAC Name2-acetoxybenzoic acid
Other namesAcetylsalicylic acid, aspirin, acetylsalicylate.
Molar mass180.16 g/mol

What is the Iupac name of aspirin?

2-Acetoxybenzoic acid
Aspirin/IUPAC ID

Is Ibuprofen A aspirin?

No. The pain reliever in Advil is ibuprofen, however both are part of the class of drugs known as NSAIDs (nonsteroidal anti-inflammatory drug).

What is the spectrum of aspirin in NMR?

It is also used in low doses in preventive treatment against heart attacks, strokes and blood clots. The 1H NMR spectrum of a 4% (w/w; 330 mM) solution of aspirin in chloroform-D was measured at 82 MHz using the Thermo Scientific™ picoSpin™ 80 NMR spectrometer.

What is picoSpin 1H NMR?

The picoSpin family of benchtop 1H NMR spectrometers can analyze a diverse range of organic compounds, allowing one to extract a wealth of chemical and structural information from high-resolution spectra.

What is the mechanism of action of acetylsalicylic acid in aspirin?

Aspirin is an orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

What is the molecular formula of aspirin?

Aspirin PubChem CID 2244 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C9H8O4 or CH3COOC6H4COOH or HC9H7O4 Synonyms aspirin ACETYLSALICYLIC ACID 50-78-2