Does blood type matter for bone marrow transplant?
Daniel Johnson
Published Feb 25, 2026
Does blood type matter for bone marrow transplant?
The HLA test looks at genetic markers on your white blood cells. If these markers are similar to those on the patient’s cells, you may be eligible to serve as a donor. You do not need to have the same blood type as the patient in order to be a donor.
Who can be a bone marrow donor match?
Everyone, age 18-44, who is in good health, and willing to donate to any patient, is encouraged to join the Be The Match Registry. Prescription hormone therapy does NOT exclude you from joining the registry.
How do they match for bone marrow transplant?
Doctors match donors to patients based on their human leukocyte antigen (HLA) tissue type. HLA are proteins, or markers, found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not.
Does bone marrow change your blood type?
This is because most of your red blood cells are made in your bone marrow. If the marrow donor has a different blood type, your blood type will eventually change to the donor’s type.
Is it hard to find bone marrow match?
A patient’s likelihood of finding a matching bone marrow donor or cord blood unit on the Be The Match Registry® ranges from 29% to 79% depending on ethnic background.
How rare is a bone marrow match?
What is the golden blood type?
Rh null blood group
The golden blood type or Rh null blood group contains no Rh antigens (proteins) on the red blood cell (RBC). This is the rarest blood group in the world, with less than 50 individuals having this blood group.
Is O Negative the rarest blood type?
Contrary to popular belief, O- blood is not the rarest blood type. It is estimated 7 percent of the population has O- blood type while only 1% of the population has AB- blood. In fact, O Negative blood is often used for premature infants and babies who need blood transfusions.
Who is the best match for bone marrow transplant?
A brother or sister is most likely to be a match. There is a 1 in 4 chance of your cells matching. This is called a matched related donor (MRD) transplant. Anyone else in the family is unlikely to match.